My size large E+1 came with 165 cranks not 170s (which I've swapped for 155s anyway).I have a medium reign E+0 2022 and have it in the low setting and very rarely get any pedal strikes with saint clipless pedals, the medium comes with 165 cranks and when I measured the BB in low it was 335mm so perhaps the larger frames are just a bit lower and with 170 cranks would cause more pedal strikes